Could there really be any other choice? For almost a decade, the husband-and-wife rock-star team of Greg and Sharon Alliferis has run this midsized venue as if it were a major-league ballroom. They regularly pack the house for big names and offer a solid sound system and friendly service to smaller fries, both important elements in creating a buzzworthy club. In 2005, though, they really honed their focus and put together a consistently eclectic, exciting roster of shows, including the Killers, Soulive, the Extreme Music Festival, Railroad Earth, and Reigning Sound. The décor is all black and perfectly sparse, kind of like a blank palette for the music, and bands tend to step up and offer topnotch performances thanks to the room's iconic history. From death metal to bluegrass to local faves to national headliners, there's no better place in South Florida to rock the hell out.