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A week-long cruise in the Caribbean and a seven-day music festival featuring top-notch performers may seem hard to combine. But, like our current cover story on the Bruise Cruise proves, setting music afloat on the high seas isn't so strange any more.

Before the Bruise Cruise, though, for the past four years the folks at musical cruise promoters Sixthman have already been putting the two together with their annual Cayamo cruises. The luxury vacations feature the best singer-songwriters around, and organizers have just announced the fifth edition of the cruise. It's scheduled to set sail from Miami from February 5 through 12, 2012. Like the four excursions before, it offers both spectacular destinations and a line-up that's clearly the envy of any festival confined to dry land.